BDBM3724 4-N-(3-chlorophenyl)-6-N-methylpyrido[3,4-d]pyrimidine-4,6-diamine::4-[(3-Chlorophenyl)amino]-6-(methylamino)pyrido[3,4-d]pyrimidine::PD158780 Analog 7b

SMILES CNc1cc2c(Nc3cccc(Cl)c3)ncnc2cn1

InChI Key InChIKey=KYQINICYADKJGN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3724   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Auckland

LigandPNGBDBM3724(4-N-(3-chlorophenyl)-6-N-methylpyrido[3,4-d]pyrimi...)
Affinity DataIC50:  0.190nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed