BDBM372417 US10245275, Compound B

SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CCC(C)(CC6)OC=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCS(=O)(=O)CC1

InChI Key InChIKey=RGJZDNVYNXKZPQ-YOEMOPHQSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372417   

TargetGag-Pol polyprotein [A364V](Human immunodeficiency virus type 1 group M subtyp...)
Viiv Healthcare UK (No. 4)

US Patent
LigandPNGBDBM372417(US10245275, Compound B)
Affinity DataEC50:  1.30E+3nMAssay Description:MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Viiv Healthcare UK (No. 4)

US Patent
LigandPNGBDBM372417(US10245275, Compound B)
Affinity DataEC50:  2nMAssay Description:MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent