BDBM372962 US9895376, Compound 1.3
SMILES Sc1ccccc1NC(=O)C1C2Cc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12
InChI Key InChIKey=WIZGJVWLGMIHPA-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 372962
TargetRAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D](Homo sapiens (Human))
Beigene
US Patent
Beigene
US Patent
Affinity DataIC50: 5.5nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair