BDBM373038 US9896418, Compound 267

SMILES O[C@H]1c2c(CC1(F)F)c(Oc1cc(c[n+]([O-])c1)C#N)ccc2S(=O)(=O)C(F)(F)F

InChI Key InChIKey=IUZOLWLYGCYSJA-AWEZNQCLSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 373038   

TargetVascular endothelial growth factor A(Homo sapiens (Human))
Peloton Therapeutics

US Patent
LigandPNGBDBM373038(US9896418, Compound 267)
Affinity DataEC50:  830nMAssay Description:About 7500 of 786-0 cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Peloton Therapeutics

US Patent
LigandPNGBDBM373038(US9896418, Compound 267)
Affinity DataEC50:  830nMAssay Description:Four hours later, serial dilutions of 10× compound stocks were made in growth medium from 500×DMSO stocks, and 20 μL of those 10× stocks were ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent