BDBM373092 1-(1-phenyl-3- pyridin-4-yl-1H- pyrazol-5-yl)-3- pyridin-2-ylurea::US9896447, Compound 9

SMILES O=C(Nc1cc(nn1-c1ccccc1)-c1ccncc1)Nc1ccccn1

InChI Key InChIKey=UFKCEHMRKHUVJM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373092   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM373092(1-(1-phenyl-3- pyridin-4-yl-1H- pyrazol-5-yl)-3- p...)
Affinity DataIC50:  350nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent