BDBM373108 1-(3-methyl-1- phenyl-1H-pyrazol- 5-yl)-3-(2- phenylimidazo[1,2- a]pyridin-3-yl)urea::US9896447, Compound 25

SMILES Cc1cc(NC(=O)Nc2c(nc3ccccn23)-c2ccccc2)n(n1)-c1ccccc1

InChI Key InChIKey=PDAADTWHSNZUMB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373108   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM373108(1-(3-methyl-1- phenyl-1H-pyrazol- 5-yl)-3-(2- phen...)
Affinity DataIC50:  520nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent