BDBM373138 US9896452, Example 3::rac-(5-Fluoro-2-((5-(trifluoromethyl)pyridin-2-ylamino)methyl)piperidin-1-yl)(2-methyl-5-phenylthiazol-4-yl)methanone

SMILES Cc1nc(C(=O)N2CC(F)CCC2CNc2ccc(cn2)C(F)(F)F)c(s1)-c1ccccc1

InChI Key InChIKey=GJDYBOVHDFWUGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 373138   

TargetOrexin receptor type 2(Homo sapiens (Human))
Eolas Therapeutics

US Patent
LigandPNGBDBM373138(US9896452, Example 3 | rac-(5-Fluoro-2-((5-(triflu...)
Affinity DataIC50:  36nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO-OX1 or CHO-OX2 cells are seeded into black-walled clear-base 384-well plates (Costar) at a density of 20,00...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Eolas Therapeutics

US Patent
LigandPNGBDBM373138(US9896452, Example 3 | rac-(5-Fluoro-2-((5-(triflu...)
Affinity DataIC50:  2nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO-OX1 or CHO-OX2 cells are seeded into black-walled clear-base 384-well plates (Costar) at a density of 20,00...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent