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BDBM373202 FD-2013025::US9902709, Compound Example 4

SMILES: Cn1cc(cn1)-c1nccc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)c1C#N

InChI Key: InChIKey=BKFNZQGBBFLGRZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373202   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM373202
PNG
(FD-2013025 | US9902709, Compound Example 4)
Show SMILES Cn1cc(cn1)-c1nccc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)c1C#N
Show InChI InChI=1S/C24H16ClF3N6O2/c1-34-13-14(12-31-34)22-18(11-29)21(8-9-30-22)36-17-5-2-15(3-6-17)32-23(35)33-16-4-7-20(25)19(10-16)24(26,27)28/h2-10,12-13H,1H3,(H2,32,33,35)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 68.5n/an/an/an/an/an/a



University of Mississippi



Assay Description
Kinase Enzymatic step assay Control (10 μL) Sample Negative Positive Compound 4 μL 4 μL 2.5% 4 μL 2.5% DMSO/kinase DMSO/kinase bu...


J Med Chem 48: 2906-15 (2005)


BindingDB Entry DOI: 10.7270/Q2T43WF5
More data for this
Ligand-Target Pair