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BDBM373272 FD-2013033::US9902709, Compound Example 7

SMILES: CNc1c(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccnc1-c1cnn(C)c1

InChI Key: InChIKey=BPWPANHJXABLEF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB:
Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373272   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM373272
PNG
(FD-2013033 | US9902709, Compound Example 7)
Show SMILES CNc1c(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccnc1-c1cnn(C)c1
Show InChI InChI=1S/C24H20ClF3N6O2/c1-29-22-20(9-10-30-21(22)14-12-31-34(2)13-14)36-17-6-3-15(4-7-17)32-23(35)33-16-5-8-19(25)18(11-16)24(26,27)28/h3-13,29H,1-2H3,(H2,32,33,35)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 656n/an/an/an/an/an/a



PEKING UNIVERSITY FOUNDER GROUP CO., LTD.

US Patent


Assay Description
Kinase Enzymatic step assay Control (10 μL) Sample Negative Positive Compound 4 μL 4 μL 2.5% 4 μL 2.5% DMSO/kinase DMSO/kinase bu...


US Patent US9902709 (2018)


BindingDB Entry DOI: 10.7270/Q2T43WF5
More data for this
Ligand-Target Pair