BDBM374629 1-(1-(2,4-Dichlorophenyl)ethyl)-6-(3′-methyl-[1,4′-bipiperidin]-1′-yl)-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyrazine hydrochloride::US10246462, Example 10
SMILES CC(c1ccc(Cl)cc1Cl)n1nc(c2ncc(nc12)N1CCC(C(C)C1)N1CCCCC1)C(F)(F)F
InChI Key InChIKey=QYVQNJGJVOKIOW-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 374629
Affinity DataIC50: 837nMAssay Description:Antagonist activity at human CCR4 expressed in rat chem-5 cells assessed as inhibition of CCL22-induced calcium flux measured at 2.5 secs time interv...More data for this Ligand-Target Pair
Affinity DataIC50: >500nMAssay Description:To measure binding of 125I-TARC or 125I-MDC to cells expressing CCR4 (e.g., CEM cells (e.g., ATCC HB-12624)), the 125I-TARC or 125I-MDC is diluted to...More data for this Ligand-Target Pair