BDBM374647 1-((R)-1-(2,4-Dichlorophenyl)ethyl)-6-((3′S,4′R)-3′-(hydroxymethyl)-[1,4′-bipiperidin]-1′-yl)-1H-pyrazolo[3,4-b]pyrazine-3-carbonitrile hydrochloride::US10246462, Example 28

SMILES C[C@H](c1ccc(Cl)cc1Cl)n1nc(C#N)c2ncc(nc12)N1CC[C@H]([C@@H](CO)C1)N1CCCCC1

InChI Key InChIKey=IRWBEMQQBZGECS-DRSNIGMVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374647   

TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Flx Bio

US Patent
LigandPNGBDBM374647(1-((R)-1-(2,4-Dichlorophenyl)ethyl)-6-((3′S,...)
Affinity DataIC50:  300nMAssay Description:To measure binding of 125I-TARC or 125I-MDC to cells expressing CCR4 (e.g., CEM cells (e.g., ATCC HB-12624)), the 125I-TARC or 125I-MDC is diluted to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent