BDBM374660 3-(1′-(1-((R)-1-(2,4-dichlorophenyl)ethyl)-3-methyl-1H-pyrazolo[3,4-b]pyrazin-6-yl)-3′-methyl-[1,4′-bipiperidin]-3-yl)propanoic acid::US10246462, Example 41

SMILES CCOC(=O)CCC1CCCN(C1)C1CCN(CC1C)c1cnc2c(C)nn([C@H](C)c3ccc(Cl)cc3Cl)c2n1

InChI Key InChIKey=XJKVQFDJKPJAPQ-YHCRIBGTSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374660   

TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Flx Bio

US Patent
LigandPNGBDBM374660(3-(1′-(1-((R)-1-(2,4-dichlorophenyl)ethyl)-3...)
Affinity DataIC50: >500nMAssay Description:To measure binding of 125I-TARC or 125I-MDC to cells expressing CCR4 (e.g., CEM cells (e.g., ATCC HB-12624)), the 125I-TARC or 125I-MDC is diluted to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent