BDBM374904 US10251893, Cpd 112

SMILES FC(F)(F)c1cc(CC(=O)Nc2ccc(cn2)-c2ccccn2)ccc1-c1ccnnc1

InChI Key InChIKey=CHNOTGUABSMKIV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374904   

TargetProtein Wnt-3a(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM374904(US10251893, Cpd 112)
Affinity DataIC50:  0.100nMAssay Description:Human embryonic kidney 293 cells (obtained from American Type Culture Collection, ATCC, Manassas, Va.) are cultured in DMEM medium (Gibco/Invitrogen,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent