BDBM375518 4-(4-cyclopropyl-1H-imidazol-1-yl)-5- (hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)- N-(2-(4-((S)-1,1,1-trifluoropropan-2-yl)-4H- 1,2,4-triazol-3-yl)thiazol-4-yl)picolinamide::US9908875, 37
SMILES C[C@H](n1cnnc1-c1nc(cs1)N(N1CC2CCCN2C(C1)n1cnc(c1)C1CC1)C(=O)c1ccccn1)C(F)(F)F
InChI Key InChIKey=WEMKKBMCJKSRPD-OYMFQORVSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 375518
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: 1.80nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection. This is a competitive, time...More data for this Ligand-Target Pair