BDBM375518 4-(4-cyclopropyl-1H-imidazol-1-yl)-5- (hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)- N-(2-(4-((S)-1,1,1-trifluoropropan-2-yl)-4H- 1,2,4-triazol-3-yl)thiazol-4-yl)picolinamide::US9908875, 37

SMILES C[C@H](n1cnnc1-c1nc(cs1)N(N1CC2CCCN2C(C1)n1cnc(c1)C1CC1)C(=O)c1ccccn1)C(F)(F)F

InChI Key InChIKey=WEMKKBMCJKSRPD-OYMFQORVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 375518   

TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM375518(4-(4-cyclopropyl-1H-imidazol-1-yl)-5- (hexahydropy...)
Affinity DataIC50:  1.80nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection. This is a competitive, time...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent