BDBM375755 US10301323, Compound A2::US9908899, Compound A2

SMILES Cn1cc(\C=C\C(=O)Nc2ccccc2N)cn1

InChI Key InChIKey=XGNVYLHZMFCYCY-VOTSOKGWSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 375755   

TargetHistone deacetylase 1(Homo sapiens (Human))
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM375755(US10301323, Compound A2 | US9908899, Compound A2)
Affinity DataIC50:  7.50E+3nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM375755(US10301323, Compound A2 | US9908899, Compound A2)
Affinity DataIC50:  1.50E+4nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM375755(US10301323, Compound A2 | US9908899, Compound A2)
Affinity DataIC50: <1.00E+3nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM375755(US10301323, Compound A2 | US9908899, Compound A2)
Affinity DataIC50:  7.50E+3nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM375755(US10301323, Compound A2 | US9908899, Compound A2)
Affinity DataIC50:  1.50E+4nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM375755(US10301323, Compound A2 | US9908899, Compound A2)
Affinity DataIC50: <1.00E+3nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent