BDBM375769 US10301323, Compound F3::US9908899, Compound F3

SMILES Nc1ccccc1NC(=O)c1ccc(C=C2CN(Cc3ccc4cc[nH]c4c3)C2)cc1

InChI Key InChIKey=YLZQVWHBPTVEHO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 375769   

TargetHistone deacetylase 1(Homo sapiens (Human))
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM375769(US10301323, Compound F3 | US9908899, Compound F3)
Affinity DataIC50: <1.00E+3nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM375769(US10301323, Compound F3 | US9908899, Compound F3)
Affinity DataIC50: <1.00E+3nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM375769(US10301323, Compound F3 | US9908899, Compound F3)
Affinity DataIC50: <1.00E+3nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM375769(US10301323, Compound F3 | US9908899, Compound F3)
Affinity DataIC50: <1.00E+3nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM375769(US10301323, Compound F3 | US9908899, Compound F3)
Affinity DataIC50: <1.00E+3nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM375769(US10301323, Compound F3 | US9908899, Compound F3)
Affinity DataIC50: <1.00E+3nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent