BDBM375874 US9914731, Ex. No. 94
SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3cc(cn4nccc34)-c3cn(C)cn3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O
InChI Key InChIKey=LTNPQCGDRQDPKT-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 375874
Affinity DataIC50: <10nMAssay Description:The cMET kinase assay was performed in 384-well Fluotrac™ 200 HiBase microplates using the HTRF KinEASE™ assay described above for AXL except that th...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The ability of compounds to inhibit the kinase activity of recombinant human baculovirus-expressed AXL was measured by homogeneous TRF (HTRF) using C...More data for this Ligand-Target Pair