BDBM375886 US9914731, Ex. No. 105
SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3cc(cn4nccc34)-c3cncs3)c(F)c2)c1=O
InChI Key InChIKey=BFUSNYLLYCPFER-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 375886
Affinity DataIC50: <10nMAssay Description:The cMET kinase assay was performed in 384-well Fluotrac™ 200 HiBase microplates using the HTRF KinEASE™ assay described above for AXL except that th...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:The ability of compounds to inhibit the kinase activity of recombinant human baculovirus-expressed AXL was measured by homogeneous TRF (HTRF) using C...More data for this Ligand-Target Pair