BDBM376009 N-(1$#8243;,5-dimethyl-1H,1$#8243;H- 3,1':3',4$#8243;-terpyrazol-5'-yl)-3- (4-methyl-1,3-thiazol-2-yl)-4- (trifluoromethyl)benzamide::US9914736, Compound 5

SMILES Cc1csc(n1)-c1cc(ccc1C(F)(F)F)C(=O)Nc1cc(nn1-c1cc(C)[nH]n1)-c1cnn(C)c1

InChI Key InChIKey=VGNNOBDTFJSTLC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376009   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376009(N-(1$#8243;,5-dimethyl-1H,1$#8243;H- 3,1':3',4$#82...)
Affinity DataIC50:  0.850nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent