BDBM376016 N-(1-methyl-4-phenyl-1H- imidazol-5-yl)-3-(1-methyl- 1H-pyrazol-3-yl)-4- (trifluoromethyl)benzamide::US9914736, Compound 12

SMILES Cn1ccc(n1)-c1cc(ccc1C(F)(F)F)C(=O)Nc1c(ncn1C)-c1ccccc1

InChI Key InChIKey=IHVQSZANXCJVDN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376016   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376016(N-(1-methyl-4-phenyl-1H- imidazol-5-yl)-3-(1-methy...)
Affinity DataIC50:  19nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent