BDBM376033 N-[1-(4-fluorophenyl)-3- pyridin-4-yl-1H-pyrazol-5-yl]- 3-(5-methyl-1,2,4-oxadiazol-3- yl)-4- (trifluoromethyl)benzamide::US9914736, Compound 29

SMILES Cc1cc(no1)-c1cc(ccc1C(F)(F)F)C(=O)Nc1cc(nn1-c1ccc(F)cc1)-c1ccncc1

InChI Key InChIKey=OZEDLQGESODLME-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376033   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376033(N-[1-(4-fluorophenyl)-3- pyridin-4-yl-1H-pyrazol-5...)
Affinity DataIC50:  530nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent