BDBM376050 2-chloro-N-(4-methyl-1- phenyl-1H-pyrazol-5-yl)-5-(1- methyl-1H-pyrazol-3-yl)-4- (trifluoromethyl)benzamide::US9914736, Compound 46

SMILES Cc1cnn(c1NC(=O)c1cc(-c2ccn(C)n2)c(cc1Cl)C(F)(F)F)-c1ccccc1

InChI Key InChIKey=DLOOXXASXBTVDE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376050   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376050(2-chloro-N-(4-methyl-1- phenyl-1H-pyrazol-5-yl)-5-...)
Affinity DataIC50:  13nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent