BDBM376055 N-[3-(hydroxymethyl)-5'- methyl-2'H-1,3'-bipyrazol-5- yl'-3-(1-methyl-1H-pyrazol-3- yl)-4- (trifluoromethyl)benzamide::US9914736, Compound 51

SMILES Cc1cc([nH]n1)-n1nc(CO)cc1NC(=O)c1ccc(c(c1)-c1ccn(C)n1)C(F)(F)F

InChI Key InChIKey=SHIOHBNZBAJSQC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376055   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376055(N-[3-(hydroxymethyl)-5'- methyl-2'H-1,3'-bipyrazol...)
Affinity DataIC50:  2.90nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent