BDBM376060 N-[3-(6-oxo-1,6- dihydropyridazin-3-yl)-1- phenyl-1H-pyrazol-5-yl]-3- pyrimidin-2-yl-4- (trifluoromethyl)benzamide::US9914736, Compound 56

SMILES FC(F)(F)c1ccc(cc1-c1ncccn1)C(=O)Nc1cc(nn1-c1ccccc1)-c1ccc(=O)[nH]n1

InChI Key InChIKey=NAZOUEVACABCAP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376060   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376060(N-[3-(6-oxo-1,6- dihydropyridazin-3-yl)-1- phenyl-...)
Affinity DataIC50:  27nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent