BDBM376081 N-[1-(4-fluorophenyl)-3-{[2- (2-hydroxyethyl)-2H-tetrazol- 5-yl]methyl}-1H-pyrazol-5- yl]-3-(1-methyl-1H-pyrazol-3- yl)-4- (trifluoromethyl)benzamide::US9914736, Compound 77

SMILES Cn1ccc(n1)-c1cc(ccc1C(F)(F)F)C(=O)Nc1cc(Cc2nnn(CCO)n2)nn1-c1ccc(F)cc1

InChI Key InChIKey=WHBHFWSEDARLSF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376081   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376081(N-[1-(4-fluorophenyl)-3-{[2- (2-hydroxyethyl)-2H-t...)
Affinity DataIC50:  14nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent