BDBM376082 N-[1-(4-fluorophenyl)-3-({2- [2-(methylamino)-2-oxoethyl]- 2H-tetrazol-5-yl}methyl)-1H- pyrazol-5-yl]-3-(1-methyl-1H- pyrazol-3-yl)-4- (trifluoromethyl)benzamide::US9914736, Compound 78

SMILES CNC(=O)Cn1nnc(Cc2cc(NC(=O)c3ccc(c(c3)-c3ccn(C)n3)C(F)(F)F)n(n2)-c2ccc(F)cc2)n1

InChI Key InChIKey=DBQZLTDWRGPIRF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376082   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376082(N-[1-(4-fluorophenyl)-3-({2- [2-(methylamino)-2-ox...)
Affinity DataIC50:  1.60nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent