BDBM376114 (5-(2-fluoro-5-(pyrimidin-2- yl)-4- (trifluoromethyl)benzamido)- 1-(4-fluorophenyl)-1H- pyrazol-3-yl)methyl carbamate::US9914736, Compound 110

SMILES NC(=O)OCc1cc(NC(=O)c2cc(c(cc2F)C(F)(F)F)-c2ncccn2)n(n1)-c1ccc(F)cc1

InChI Key InChIKey=XNTGKZVGOYJEJF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376114   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376114((5-(2-fluoro-5-(pyrimidin-2- yl)-4- (trifluorometh...)
Affinity DataIC50:  7nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent