BDBM376355 (R)-N-(1-(2- chlorophenyl) ethyl)-6H- isochromeno[3,4-c] pyridine-8- carboxamide::US9914740, VI-5

SMILES C[C@@H](NC(=O)c1ccc-2c(COc3cnccc-23)c1)c1ccccc1Cl

InChI Key InChIKey=USLFLIWOEFKGJX-CYBMUJFWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376355   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376355((R)-N-(1-(2- chlorophenyl) ethyl)-6H- isochromeno[...)
Affinity DataIC50:  2.80nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent