BDBM376441 6-ethyl-N-[(1R)-1-(3- methoxyphenyl)ethyl]- 6H-isochromeno[3,4-c] pyridine-8-carboxamide::US9914740, XI-16::US9914740, XI-17

SMILES CCC1Oc2cnccc2-c2ccc(cc12)C(=O)N[C@H](C)c1cccc(OC)c1

InChI Key InChIKey=TUQZDIZIVRTIGP-JGHKVMFLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 376441   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376441(6-ethyl-N-[(1R)-1-(3- methoxyphenyl)ethyl]- 6H-is...)
Affinity DataIC50:  0.180nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376441(6-ethyl-N-[(1R)-1-(3- methoxyphenyl)ethyl]- 6H-is...)
Affinity DataIC50:  0.520nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent