BDBM376488 (R)-N-(1-(3- methoxyphenyl)ethyl)-9- methyl-9H-pyrido[3,4-b] indole-7-carboxamide::US9914740, XIV-9

SMILES COc1cccc(c1)[C@@H](C)NC(=O)c1ccc2c(c1)n(C)c1cnccc21

InChI Key InChIKey=UYWYQQVLMBMSSZ-CQSZACIVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376488   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376488((R)-N-(1-(3- methoxyphenyl)ethyl)-9- methyl-9H-pyr...)
Affinity DataIC50:  2.32nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent