BDBM376595 4-[5-(6-Methyl-7-oxo-6,7-dihydro-1H- pyrrolo[2,3-c]pyridin-4-yl)-4-phenoxy-1H- benzimidazol-1-yl]butanenitrile::US9918990, Example 52

SMILES Cn1cc(-c2ccc3n(CCCC#N)cnc3c2Oc2ccccc2)c2cc[nH]c2c1=O

InChI Key InChIKey=YWRZSYMDHLIIPV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 376595   

TargetBromodomain-containing protein 2(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM376595(4-[5-(6-Methyl-7-oxo-6,7-dihydro-1H- pyrrolo[2,3-c...)
Affinity DataIC50: <100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM376595(4-[5-(6-Methyl-7-oxo-6,7-dihydro-1H- pyrrolo[2,3-c...)
Affinity DataIC50: <100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent