BDBM376861 (R)-(2-((4-(2-hydroxypropan-2- yl)-5-methyloxazol-2- yl)methyl)piperidin-1-yl)(3- (pyridin-2-yl)pyrazin-2- yl)methanone::US9920038, 22

SMILES Cc1oc(C[C@H]2CCCCN2C(=O)c2nccnc2-c2ccccn2)nc1C(C)(C)O

InChI Key InChIKey=LBMNBYJPXZBVBT-MRXNPFEDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 376861   

TargetOrexin/Hypocretin receptor type 1(Rattus norvegicus (Rat))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376861((R)-(2-((4-(2-hydroxypropan-2- yl)-5-methyloxazol-...)
Affinity DataIC50:  2.93E+3nMAssay Description:For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376861((R)-(2-((4-(2-hydroxypropan-2- yl)-5-methyloxazol-...)
Affinity DataIC50:  558nMAssay Description:For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent