BDBM376999 7-[2-Methoxy-4-trifluoromethylphenyl]-6-methyl-N-[4-(piperidin-4-yl)-2,3-dihydro-1-benzofuran-7-yl]thieno[3,2-d]pyrimidin-2-amine ::US10259816, Compound 18::US10611770, Compound 18
SMILES COc1cc(ccc1-c1c(C)sc2cnc(Nc3ccc(C4CCNCC4)c4CCOc34)nc12)C(F)(F)F
InChI Key InChIKey=IJWPFPOMWIGZEJ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 376999
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Guangzhou Maxinovel Pharmaceuticals
US Patent
Guangzhou Maxinovel Pharmaceuticals
US Patent
Affinity DataIC50: 9.10nMAssay Description:Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Guangzhou Maxinovel Pharmaceuticals
US Patent
Guangzhou Maxinovel Pharmaceuticals
US Patent
Affinity DataIC50: 9.10nMAssay Description:Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel...More data for this Ligand-Target Pair