BDBM377099 US10259811, Example 212
SMILES C[N]1=CC=[N](C=C1)c1ccc(cc1)-c1nc2c(ncnc2[nH]1)-c1ccc(OC2CCOCC2)c(c1)C#N
InChI Key InChIKey=BBHVCPIWNOWNHR-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 377099
Affinity DataIC50: 1.14nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: 1.08nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair