BDBM377115 3-[9-[1-(4-amino-3-methyl- 1H-pyrazolo[3,4- d]pyrimidin-1-yl)ethyl]-7- chloro-6-cyano-2-methyl- 2,3-dihydro-1,4- benzoxazepin-4(5H)-yl]-N- ethylazetidine-1- carboxamide::US10259818, Example 97::US9944646, Example 98

SMILES CCNC(=O)N1CC(C1)N1C[C@H](C)Oc2c(cc(Cl)c(C#N)c2C1)C(C)n1nc(C)c2c(N)ncnc12

InChI Key InChIKey=SFQPBTXIJDMAGT-CFMCSPIPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 377115   

LigandPNGBDBM377115(3-[9-[1-(4-amino-3-methyl- 1H-pyrazolo[3,4- d]pyri...)
Affinity DataIC50: <100nMAssay Description:[γ-33P]ATP (10mCi/mL) was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase substrate, D-myo-Phosphatidylinositol 4,5-bisphosphate (Ptd...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM377115(3-[9-[1-(4-amino-3-methyl- 1H-pyrazolo[3,4- d]pyri...)
Affinity DataIC50: <100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent