BDBM377277 US10265310, Example 24::rac-trans-1-(4-chlorophenyl)-3-(1-(cyclopropylmethyl)-4-(4-methoxyphenyl)-6-oxopiperidin-3-yl)urea

SMILES COc1ccc(cc1)[C@H]1CC(=O)N(CC2CC2)C[C@@H]1NC(=O)Nc1ccc(Cl)cc1

InChI Key InChIKey=DRNMDGQQUPLDBA-RTWAWAEBSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 377277   

TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
GrÜNenthal

US Patent
LigandPNGBDBM377277(US10265310, Example 24 | rac-trans-1-(4-chlorophen...)
Affinity DataEC50:  500nMAssay Description:Cryo-vial containing 6×106 cells (hFPR1-Gα15-CHO or hFPR2-Aq-CHO) was thawed in a 37° C. water bath. Cells were suspended in 10 ml of respective...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
GrÜNenthal

US Patent
LigandPNGBDBM377277(US10265310, Example 24 | rac-trans-1-(4-chlorophen...)
Affinity DataEC50: <1nMAssay Description:Cryo-vial containing 6×106 cells (hFPR1-Gα15-CHO or hFPR2-Aq-CHO) was thawed in a 37° C. water bath. Cells were suspended in 10 ml of respective...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent