BDBM377521 4-{[1-(6-chloro-2-oxo-1,2-::US10266495, Compound I-1
SMILES COc1cc(NC(C)c2cc3cc(Cl)ccc3[nH]c2=O)ccc1C#N
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 377521
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Sunshine Lake Pharma
US Patent
Sunshine Lake Pharma
US Patent
Affinity DataIC50: 55nMAssay Description:Assays were performed in a 384-well black plate. An aliquot of 250 nL of compound was incubated with 10 μL of 30 nM IDH1-R132H or 10 nM IDH1-R13...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
Sunshine Lake Pharma
US Patent
Sunshine Lake Pharma
US Patent
Affinity DataIC50: 55nMAssay Description:Assays were performed in a 384-well black plate. An aliquot of 250 nL of compound was incubated with 10 μL of 30 nM IDH1-R132H or 10 nM IDH1-R13...More data for this Ligand-Target Pair