BDBM377617 4-{[(7-chloro-2-oxo-1,2-::US10266495, Compound I-29

SMILES COc1cc(NCc2cc3ccc(Cl)cc3[nH]c2=O)ccc1C#N

InChI Key InChIKey=TXZUSOMDIDEBSP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 377617   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM377617(4-{[(7-chloro-2-oxo-1,2- | US10266495, Compound I-...)
Affinity DataIC50:  550nMAssay Description:Assays were performed in a 384-well black plate. An aliquot of 250 nL of compound was incubated with 10 μL of 30 nM IDH1-R132H or 10 nM IDH1-R13...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent