BDBM377642 2-methoxy-4-{[(7-methyl-2-oxo-1,2-dihydroquinolin-3-::US10266495, Compound I-54

SMILES COc1cc(NCc2cc3ccc(C)cc3[nH]c2=O)ccc1C#N

InChI Key InChIKey=HYZMLMIAPFRYEP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 377642   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM377642(2-methoxy-4-{[(7-methyl-2-oxo-1,2-dihydroquinolin-...)
Affinity DataIC50:  550nMAssay Description:Assays were performed in a 384-well black plate. An aliquot of 250 nL of compound was incubated with 10 μL of 30 nM IDH1-R132H or 10 nM IDH1-R13...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent