BDBM378877 US10266535, Compound 76

SMILES CN(C)CC(=O)NC1CCC(CC1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12

InChI Key InChIKey=XRQOHJAXNKKVKL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 378877   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Hefei Institutes Of Physical Science, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM378877(US10266535, Compound 76)
Affinity DataIC50:  16nMAssay Description:In the experiments of in vitro enzymatic activity, the IC50 values of Compound 33, Compound 30, Compound 14, Compound 20, Compound 22, Compound 23, C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hefei Institutes Of Physical Science, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM378877(US10266535, Compound 76)
Affinity DataIC50:  388nMAssay Description:In the experiments of in vitro enzymatic activity, the IC50 values of Compound 33, Compound 30, Compound 14, Compound 20, Compound 22, Compound 23, C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDimer of Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Hefei Institutes Of Physical Science, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM378877(US10266535, Compound 76)
Affinity DataIC50:  478nMAssay Description:In the experiments of in vitro enzymatic activity, the IC50 values of Compound 33, Compound 30, Compound 14, Compound 20, Compound 22, Compound 23, C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent