BDBM379167 N-Methyl-2-(5-phenyl-2-(3,4,5-trimethoxyphenylamino) pyrimidin-4-ylamino)benzamide::US10266549, Example 73::US10774092, Example 73

SMILES CNC(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1-c1ccccc1

InChI Key InChIKey=ZDHQQZXYBJCSQV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 379167   

TargetSerine/threonine-protein kinase ULK1(Homo sapiens (Human))
Salk Institute For Biological Studies

US Patent
LigandPNGBDBM379167(N-Methyl-2-(5-phenyl-2-(3,4,5-trimethoxyphenylamin...)
Affinity DataIC50: <200nMAssay Description:ULK1 inhibition assay is a screening assay to identify compounds that inhibit kinase activity of ULK1 using the ULKtide peptide. In some embodiments,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase ULK1(Homo sapiens (Human))
Salk Institute For Biological Studies

US Patent
LigandPNGBDBM379167(N-Methyl-2-(5-phenyl-2-(3,4,5-trimethoxyphenylamin...)
Affinity DataIC50: <200nMAssay Description:Gamma-32P assays to measure ULK1 kinase activity were performed as previously described. Briefly, Flag ULK1 was transfected into HEK293T cells and 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent