BDBM379471 US10266550, Compound 11f
SMILES Nc1ccc2c(c1)oc1c(NC34CC5CC(CC(C5)C3)C4)c(F)cc3c1n2cc(C(O)=O)c3=O
InChI Key InChIKey=NJZLURAWJQPZSM-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 379471
TargetDNA topoisomerase 1(Escherichia coli (strain K12))
The Florida International University Board Of Trustees
US Patent
The Florida International University Board Of Trustees
US Patent
Affinity DataIC50: 5.85E+3nMAssay Description:The relaxation activity of E. coli topoisomerase I was assayed in a buffer containing 10 mM Tris-HCl, pH 8.0, 50 mM NaCl, 0.1 mg/mL gelatin, and 0.5 ...More data for this Ligand-Target Pair