BDBM379471 US10266550, Compound 11f

SMILES Nc1ccc2c(c1)oc1c(NC34CC5CC(CC(C5)C3)C4)c(F)cc3c1n2cc(C(O)=O)c3=O

InChI Key InChIKey=NJZLURAWJQPZSM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 379471   

TargetDNA topoisomerase 1(Escherichia coli (strain K12))
The Florida International University Board Of Trustees

US Patent
LigandPNGBDBM379471(US10266550, Compound 11f)
Affinity DataIC50:  5.85E+3nMAssay Description:The relaxation activity of E. coli topoisomerase I was assayed in a buffer containing 10 mM Tris-HCl, pH 8.0, 50 mM NaCl, 0.1 mg/mL gelatin, and 0.5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent