BDBM379478 US10266550, Compound 15a

SMILES CC(C)(C)OC(=O)NC1CCN(C1)c1c(F)cc2c3c1oc1cc(N)ccc1n3cc(C(O)=O)c2=O

InChI Key InChIKey=HIUKBFZTUNSISE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 379478   

TargetDNA topoisomerase 1(Escherichia coli (strain K12))
The Florida International University Board Of Trustees

US Patent
LigandPNGBDBM379478(US10266550, Compound 15a)
Affinity DataIC50:  3.90E+3nMAssay Description:The relaxation activity of E. coli topoisomerase I was assayed in a buffer containing 10 mM Tris-HCl, pH 8.0, 50 mM NaCl, 0.1 mg/mL gelatin, and 0.5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent