BDBM380182 6-[2- (dimethylamino)ethoxy]- N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)phenyl]pyrazolo[1,5- a]pyridine-3- carboxamide::US9926282, Example 177

SMILES CN(C)CCON(C(=O)c1cnn2ccccc12)c1ccc(cc1)-c1n[nH]c(=O)c2ccccc12

InChI Key InChIKey=YBHWBVDYOLITDW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 380182   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM380182(6-[2- (dimethylamino)ethoxy]- N-[4-(4-oxo-3,4- dih...)
Affinity DataIC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM380182(6-[2- (dimethylamino)ethoxy]- N-[4-(4-oxo-3,4- dih...)
Affinity DataIC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent