BDBM380187 5-methoxy-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl)phenyl]pyrazolo[1,5- a]pyridine-3- carboxamide::US9926282, Example 182

SMILES COc1ccn2ncc(C(=O)Nc3ccc(cc3)-c3n[nH]c(=O)c4ccccc34)c2c1

InChI Key InChIKey=NTZMHDIJCNVDNP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 380187   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM380187(5-methoxy-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl...)
Affinity DataIC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM380187(5-methoxy-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl...)
Affinity DataIC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent