BDBM380558 6-methyl-N-{4- [4- (trifluoromethyl)- piperidin-1- yl]cyclohexyl}- quinazolin-4-amine::US9926330, 2-11

SMILES Cc1ccc2ncnc(NC3CCC(CC3)N3CCC(CC3)C(F)(F)F)c2c1

InChI Key InChIKey=KTUYOCPUJSUXLD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380558   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM380558(6-methyl-N-{4- [4- (trifluoromethyl)- piperidin-1-...)
Affinity DataIC50:  88nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent