BDBM380576 US9926330, 2-29::trans-N-(2,2- dimethylpropyl)-N'-(6- methylquinazolin-4- yl)cyclohexane-1,4- diamine

SMILES Cc1ccc2ncnc(N[C@H]3CC[C@@H](CC3)NCC(C)(C)C)c2c1

InChI Key InChIKey=GAEFYCDPAFEPQX-WKILWMFISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380576   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM380576(US9926330, 2-29 | trans-N-(2,2- dimethylpropyl)-N'...)
Affinity DataIC50:  69nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent