BDBM380592 4-((trans)-4-(((6-methylquinazolin-4-yl)amino)cyclohexyl)thiomorpholine-1,1-dioxide ::US9926330, 6-1

SMILES Cc1ccc2ncnc(N[C@H]3CC[C@@H](CC3)N3CCS(=O)(=O)CC3)c2c1

InChI Key InChIKey=LGNKVHCAYRXISB-WKILWMFISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380592   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM380592(4-((trans)-4-(((6-methylquinazolin-4-yl)amino)cycl...)
Affinity DataIC50:  623nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent