BDBM380594 4-(4-(((trans)-4-Morpholinocyclohexyl)amino)quinazolin-6-yl)butan-2-ol ::US9926330, 7-1

SMILES CC(O)CCc1ccc2ncnc(N[C@H]3CC[C@@H](CC3)N3CCOCC3)c2c1

InChI Key InChIKey=WHSZCMCCYSKBCB-YGXOWLSWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380594   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM380594(4-(4-(((trans)-4-Morpholinocyclohexyl)amino)quinaz...)
Affinity DataIC50:  62nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent