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BDBM38067 US10093646, Example 15

SMILES: Oc1cn2c([nH]c(=O)c3ccccc23)c1-c1ccccc1

InChI Key: InChIKey=HBQIQEAWJXNAKF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 38067   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein phosphatase non-receptor type 11


(Homo sapiens (human))
BDBM38067
PNG
(US10093646, Example 15)
Show SMILES Oc1cn2c([nH]c(=O)c3ccccc23)c1-c1ccccc1
Show InChI InChI=1S/C17H12N2O2/c20-14-10-19-13-9-5-4-8-12(13)17(21)18-16(19)15(14)11-6-2-1-3-7-11/h1-10,20H,(H,18,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 75n/an/an/an/a7.225



Novartis AG

US Patent


Assay Description
More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...


US Patent US10093646 (2018)

More data for this
Ligand-Target Pair